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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e708da452c159dfed4953f88abd22f28b0c6354ad6e84e8e1032e85eb4256fd' 
  AND token = 'XsXb1SHnfOtM/fNVfFc7814NwZwp1ViI1GyJXVl6ZIg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}