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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a788a0380b391185e04a002c17e7f4a724d122e94dba080462b6c51da2e96522' 
  AND token = 'xQ2sqSZg+IEsxNV9WmwrlZ5Jg60rP8BogjtdexunTPc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}