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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49dba0aa8c56ff6730fb2981df76021446d36edf43db72b4bcd1e8bfd8e558af' 
  AND token = 'l4zq2GrcfRdfjh42kVqlWF4/50JyCmFX2wZfazfE+d0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}