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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c3d217fc9401446e8ee548a331e782e4a26a1f3bf1952d19727e61b239c7279' 
  AND token = 'U6Xy1u0qQjTLwEiIFoxG50wZaoPSvTvjEsfzG9LlZ94=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}