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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3a3c142700d237defa47812aa3fe9b0d93b795ffb80e25cce8e2de631504da2' 
  AND token = 'Jbnm/PraG9XIJOZ47283IKwmftMnwCcwQf6SlVL7CB8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}