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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43147c815fddf2e653b84bf83434e0147db906b3186ccbea2813cadc2b17cbf4' 
  AND token = 'hI1MSMs605PTj8YUUCpq/4piWNz6tkpozrcyBeNK5aA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}