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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '73111167290a6e494b68d1fe445dbb5ac969049539712c9065a4a2714e5d5c1a' 
  AND token = 'AiXCh+dmsv05CDbWl1HfLY+Vqt2w/SHSzxUmX+IbH2I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}