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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2debd2ee6065c6c1648b2f373093029f7f1f45c9f5eb576a7039d8c4630d3658' 
  AND token = 'XMnNJey/5eRy50EI/hyJumoztVO+wp6GATk2nODCuqk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}