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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5144b0c2d0489cc74242a70df29f9705fc0a083279cb80e1c177b23f67d6789' 
  AND token = 'ZVf2zLo7KmVNkWwkBIkzcD2MAg5uwsfH6LAKA9Rc9EI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}