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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48f638a6c206a0c3e3d262482fd9dff92941930024929f3558961c8b076c2827' 
  AND token = 'uA+gkOS7R2LrmpgUjjy4CnI4fnDrnVxrY33n3aoRBw8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}