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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b08538edc3e1c825af60d6f00fc0a4f5b636e6eb48743065063bb1d2ed44b2c' 
  AND token = 'LhN7tIIA60Sz15wldeiXSwcQGkIIW8vkR3Nq9ZIJTU8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}