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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a8886e76f97574b2ba17c0ef57a027d23cbc5bf57ad752064a4176200285663e' 
  AND token = '+GWrnxNsysux1gvdeXTgMRnCpg3IoClSZGGjrplQ9ps=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}