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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80b3d0c5e51f13857f77d4d2fe66520667d30e3abb9b7bae60efa9ed87cf3a3d' 
  AND token = 'wqTE0tELTKSRpfYJR7c2rIc3x4nAHVY9v09rcz65d6c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}