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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81b65e7bc676cf67056a3cfb1fb8db94dca7bd96bfef32d514bad5b2f1c7e264' 
  AND token = 'jj2qoopgGW+1SU//CJ81HZoi4JEatCi8Kbkj8PL12HI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}