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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e27c258bf747173c2facc4b7e246678ae94f7c63c9068a614efaf7f38475ac8' 
  AND token = 'yGK5rdLFMkJ48Ji/7uJ5v6/Aq2RJ+6VytOI2vBG08dU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}