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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4395e86ab9fe3c2a0d4be52590fc39d9be59f02024f6686612adee61000be504' 
  AND token = 'Xsaqa0a4m7gHPwszRSh0ALAfpLS1oPp1gkacLFIiC2M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}