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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b391291f5e6d65be70563dec9fbfa6cefc8cee24fdd07b69c339bc5382238559' 
  AND token = '88+JK+JcK5vnL2Y9jraRXZlzONJrDY06boI0S3yLXDE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}