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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f5133c4512e7fd62f18b6f0b307cea22047fafdae5608e392bb4f76503c045d' 
  AND token = 'HJi52gT702b0mqTa2cibzKVI9SeXoVc2iW8XkpZ+lsg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}