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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f54a5a0ab1c7b761c032d36fec892215ed71690e4c6a2145a5bb9bd8aa45f806' 
  AND token = 'EZF33j4Ori0eUDtDQyTi1HdXJNTDfsYdhrbnQT2Eqzw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}