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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b16f21ce7e4e9f95127aa17d1a3e79a865ad97e8613aeb3e262b840b32ab5b37' 
  AND token = 'TGF9FsJDsRciITXNhuBbE3Cqt9db4OJz2Qia6qSHcpU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}