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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53b1c50181e7508920df4f7b9d423f71ad2fc261877241dca121f2d46e2eeef3' 
  AND token = 'NteE1LxOwk/+q2CUie+Aa1aH5ErLFt3uu6I03eahTpw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}