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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'da05b4183be06a9f2fa529211e7bc6735f9e880ee5d1564bf73a7b5c96627f0c' 
  AND token = 'xaWT66Pb2c8Kmv1/+j9cbcM211kBDLMOgGfVRCSY7i4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}