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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c45c5b23be2420907284a7d72b9186df1f4d80178c700ebb55e2260407e56480' 
  AND token = 'mCIaz+Jv/qHIqmvD0DKS1ZiQfwb7vayHqTj6cK8gx0k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}