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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df321e59bae488c6ac5fa92ac6b3d688a7ec2c3e7d602c016a3b2ae975ba0bc6' 
  AND token = 'Wm1jd9gUxpzfQ9dNCbSnYCamFND4vYOCFPlPM7BrNq4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}