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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f648d1f64515898befbb596d56c18f65f566aa8dc1253ce0b83f096430a3b5c9' 
  AND token = 'GNzm9W7x3zfCZ/RqQWUtWQ2e4vnckJQv/ruebrRjC38=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}