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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f8e350d0cdc41d951012cfe6660864b32cec9a89e58041d1fa16521efa084dad' 
  AND token = '2RUDh1a53SSiEJENQ3OpT5J3D0yMYKCsh76TyPurxNk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}