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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00e4cd3e46984528d6ecf1301b5d8a1135d2d3448e307db8140735800e68cb45' 
  AND token = 'DchH3roNv4z3XA6GFGOlC8uU2iObXwSGuEY0Fq8dViY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}