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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a1870ff218ca000b88839c3c3d2022c72e3ed499d1b0b637e6dae24b1423c7d' 
  AND token = '8Di9pVFl6WtQSaL+n3JzB4SfWhnQbQd/OZpXLWA/yFI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}