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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9b54b67bd848ed8a43c6de4c0477bec9ec880102d28bd0bccf6fcb82ad87425a' 
  AND token = 'lTudNznHdj0M+0opgfIbloz5nYtKXHQpGc6SpfV3lLA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}