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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81c3b5ecf393341b19012936effc4850c8fad20402542629fde39caa6288da8e' 
  AND token = '4Ug721/EX3H05WmclNS2Sp+2e1a0JXpx6noaYmcOw8M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}