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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '51eb2ca42da4b9b0b00e87be4d6924da823d9c6bb8974033bcfbcc5d526b0aa9' 
  AND token = 'jrVGehxobIUjLVc+YJMJ3LdenSNbMEjta/Y+hAtKYPo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}