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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41d2748fe2d36665e973d840cc36e3a68bd18c89f357a5ca8438221c1956ca9f' 
  AND token = 'Ov4LYhaotrdRSZPx/QOMV/0BEAc4F+aVZH38w/8w57o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}