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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e07a00d1d22aee76a6356945267b73426daa0cabd52fdf398d2e82cb82631c22' 
  AND token = '3yNEmm79ZB53eAho+tUG9Gl9R+Kt/ebnDG9du69ltLk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}