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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '187d7b075b2877203c8f1129c22ea7bb8d2d860db902565b010020d6242f7c5d' 
  AND token = 'zTs+kzqjPCSeCh+cM5naOoDbXQeo0AbFnqE12AHfRIM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}