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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd95a1a42eddc77943495fc32d1aee717d944d384315f3467cefbbd2992070111' 
  AND token = 'OiZ6N55Keb/wklxAi8BVZZtOyjDEoaL/ZhrZ04qIGj0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}