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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd7e157e92f96a16bf8631de80e9716f11679bfa112a2f093ead8ce79611e710d' 
  AND token = 'd8D/FocnWVV6SW4rDnPjsW8rcUfQ4rYoSc/bS9480sM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}