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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54f075c8fb4d0df055972b1a881a6689377b262d2c82d2161f41b19840ed5dd7' 
  AND token = 'ltYAbVY6oe6uUSSACfr5+KtfiI+44fKmODWE0uS2HuY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}