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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7997fb43af5dde7488bce2fc2578e9380505e175cbbed604734e57e9eb0cc18a' 
  AND token = '7+phQECsOJ111Qr5Yt9Vrw2u06d8W2/mfwyFizTxEHw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}