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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e263f384e801716d37f80eb4e42c3e16e0f14b10156c9b0cdcd3fd83551059c6' 
  AND token = 'YkXOLV1lnofRzR4B+isp207Hz4nlQ2ZZOeWHqNMPmT8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}