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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f0a506d71ad137083ff1547374ac168ee30160855b5e9aff75cf8fed91ffe71' 
  AND token = 'iEELpuKKKXZQg6WRDvevEWxZfwt+u+Km45MhlI0KCEI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}