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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f506e2adda769507708ea3afee4077221ab5ce425c147c2be6c74e424da14beb' 
  AND token = '6NotKMhKnP1x008jbVCc7xYzKYPFsbK2X29ugyff+gM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}