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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a38fa1845710ea69cc674cb1c2cf7bb37429b122ed6c57dad9a53da86b93a62' 
  AND token = 'LgAETenDXTEDhERV2DLThXc2gC2py2UTuNdlBl0KGQI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}