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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6dceef7f35497c8012a44a041b9d75677d348431ce447eb6ed6d79671d86704a' 
  AND token = 'ksXn10yzzpKsWgSxTAISuUMWc14snbnrRHqKX2EFaiU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}