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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b5f84bffe48ddcdbe1e16610358ef1fd26d8d103ad019560e78ebfb66ba766d9' 
  AND token = 'jQBqkvdfarbK1WpgdxVP7x26ReJIkGGHFcQJ1ip+ByM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}