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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af6fdff62002d6278befc79457dfbfad8d8bfdcd049f68b7b2cba9e121566da0' 
  AND token = 'fjKgm/+h7Coq6ya/oWIgyTmCQz060O1Ll0rOXLQrheQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}