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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd99379b7c52cf49d9a164cd599d428772ea3d1079e0ea099af76978c0c638a74' 
  AND token = 'DUk7tE039JaA+Uc1JR/l9Y35UyBWzpKFjLgwpaPO9rs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}