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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f8ff56fc18af53a448ee4185129187bcbe9587691de49e14e0177c0e377d508' 
  AND token = 'QvDUM/4l/IM6cM65eHrbxialy6Sr3/iGP/JrxGd+3Gs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}