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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e84643f0421c91d5eb88b672e22cd0acf7c5ad1b709107930f222faf0323f1e' 
  AND token = 'A6OpiT/Bo0Pb6uTiZWGZuNI8TQcxSOObdtVmZQBS7R4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}