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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e6b833249fe38eed7946c52a2006ba65d050dfbd654b3fc07f9309aecc6ee3a' 
  AND token = 'T/fwt9zSA9d1E9ikXCFZWA2ZPEMRK9aIRaaU8Glga0Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}