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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd3bf019b2d64a1951605ea08f4e0bbd31c49121fe4ac15b28597385af538b3ff' 
  AND token = 'af1Oi8+PtJ143I0BIU5quW6NVrr5KEENkdisj0sZIvs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}